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As a single mg or 40 mg oral dose, the inhibitory effect of aprepitant on CYP3A4 is weak, Tadalafil 5mg the AUC of midazolam increased by 1. After administration, Cialis is rapidly converted to aprepitant and shares many of the same drug interactions.

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This medicine interacts with other medicines like Amlodipine, Carbamazepine, Ketoconazole, Phenytoin, Nitroglycerin and Cimetidine. This interaction may harm efficiencies of both medicines.

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Because of insufficient information in patients with severe hepatic impairment, use of Cialis in this group is recommended [see in Specific Populations 8. Cialis for once daily use has not been extensively evaluated in patients with mild or moderate hepatic impairment.

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